Ive been giving this to my Shizhu for about two weeks, once a day, he has developed arthritis and inflammation causing him to not put weight on his back legs. The vet recommended cortisone type shots for him twice a week and it was just super pricy so I decided to try this route first. Cannot complain, after two weeks he's starting to run short distances, he's climbing up the stairs, not fully recovered by any means but he looks to have more strength and less discomfort in his hind legs. It definitely helped the recovery process. I personally give him 1.0ml once a day in his food. He doesn't seem to mind the taste which is a good sign because he HATES medications of any type, his flea and tick stuff gets smushed into his food but he spits out the tiny miniscule chunks that don't blend. All around good product will recommend to anyone with dogs having arthritis pains.